Tom Earnest

This study uses multimodal normative modeling on ATN biomarkers to analyze Alzheimer Disease heterogeneity, finding greater intra-group variation in more severe stages and a correlation between disease severity index and cognitive decline.

This study shows that oral oxycodone self-administration in mice leads to features of opioid addiction, including escalation, dependence, and relapse behavior.

This paper introduces an oral oxycodone self-administration paradigm in mice to model prescription opioid use and its transition to abuse.

This study identifies a specific subpopulation of ventral pallidal neurons that modulate nucleus accumbens firing to enhance reward consumption.