Hendrik Wildner

This study shows nerve injury shifts spinal circuit recruitment from inhibitory to excitatory parvalbumin interneurons, causing mechanical allodynia.

The paper identifies a GABAergic pathway from the RVM to the spinal dorsal horn that mediates bilateral antinociception and is involved in pain control.

The paper identifies two functionally distinct serotonergic neuron populations in the hindbrain that have opposing effects on nociception by targeting different spinal regions.

The paper identifies CCK+ S1-CST neurons as a major cortical input to the spinal dorsal horn and characterizes their synaptic connections and molecular diversity.

The paper uses TRAP to analyze translatomes of excitatory and inhibitory neurons in mouse spinal cords, finding neuropeptide genes associated with modality-specific processing and showing little translatome change in neuropathic pain.