Federico Gaiti

This study maps somatic mutations in B-cell subsets of SLE patients, finding high mutational burden in double-negative B cells linked to disease duration and therapy.

The paper identifies four epithelial transcription states in pancreatic cancer and links their origins to early developmental processes.

This study shows chemotherapy reshapes clonal architecture in breast cancer xenografts by selecting for chemotherapy-resistant clones and stress response programs.

iSHARC is a pipeline for analyzing scMultiome data, enabling quality control, integration, clustering, annotation, and regulatory analysis in cancer studies.