Anne D. Donaldson

The paper identifies RIF1-Long as a BRCA1 binding partner that enhances RAD51-dependent repair during DNA replication stress.

This study identifies phosphorylation of RIF1's intrinsically disordered region as essential for protecting nascent DNA at stalled replication forks during replication stress.

This study shows that replication timing (RT) is essential for maintaining the global epigenetic state and genome compartmentalization in human cells, with RIF1 playing a central role in this process.

This study identifies RIF1-Long's role in promoting G1 phase 53BP1 nuclear bodies to protect against replication stress and enhance cell survival.

This study identifies that phosphorylation of Rif1 by checkpoint kinases protects nascent DNA from degradation by Sgs1-Dna2 in budding yeast, highlighting a conserved mechanism for genome stability.