Author

Leonore Wigger

SIB Swiss Institute of BioinformaticsORCID 0000-0001-5230-0265Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andreas DahliD· 1 shared Andreas‐David BrunneriD· 1 shared Anke M. Schulte· 1 shared Bernard ThorensiD· 1 shared Camille KessleriD· 1 shared Charlotte N. HoriD· 1 shared Christian D. KloseiD· 1 shared Christos Polysopoulos· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Andreas DahlORCID

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3 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJan 11, 2024

Cortical miR-709 links glutamatergic signaling to NREM sleep EEG slow waves in an activity-dependent manner

Konstantinos Kompotis, Géraldine M. Mang, Jeffrey T. Hubbard…·Paul Franken

This study shows that miR-709 regulates NREM sleep EEG slow waves by linking glutamatergic signaling to neuronal activity through endosomal trafficking.

5 citations

mouseelectronic health records

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BioinformaticsNature MetabolismPeer-reviewedJun 28, 2021

Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes

Leonore Wigger, Marko Barovic, Andreas‐David Brunner…·Michele Solimena

This study uses multi-omics analysis of pancreatic islet donors to show heterogeneous beta cell changes associated with type 2 diabetes progression.

162 citationstop 1%

humanbulk RNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedFeb 7, 2019

Sensory neuron lineage mapping and manipulation in the Drosophila olfactory system

Phing Chian Chai, Steeve Cruchet, Leonore Wigger, Richard Benton

The paper maps sensory neuron lineages in Drosophila olfactory system and identifies Pointed's role in determining cell fates through genetic and transcriptomic analysis.

41 citations

Drosophilaexperimental assay

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