Phillip Chapman

Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis

The paper shows that spinal neuron diversity increases exponentially during frog metamorphosis as motor behavior shifts from swimming to limb use, with molecular similarities to mammalian circuits.

The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output

The paper presents a single-nucleus transcriptomic atlas of spinal V1 interneurons across development, identifying En1's role in specifying a subset of V1Pou6f2 interneurons and its impact on locomotor output.

A Novel Single Vector Intersectional AAV Strategy for Interrogating Cellular Diversity and Brain Function

The paper introduces ConVERGD, a single-construct intersectional AAV strategy for targeting specific cell populations, and demonstrates its use in targeting NE+ LC neurons expressing Pdyn in rodents.