Verian Bader

This paper develops a single-domain antibody specific for M1-linked ubiquitin chains, enabling their detection and analysis across multiple applications.

The paper identifies oxidized MIF as a drug target that links HSV-1 infection and external stressors to tau pathology in Alzheimer's disease.

The paper investigates microglial dynamics and modulation in MS models using siponimod, showing reduced neuronal damage and changes in microglial markers.

This study shows that membrane anchors prevent protein misfolding and aggregation by restricting conformational freedom, with implications for prion diseases.

This paper introduces a new drug-like small molecule series targeting PDI in a multi-protein complex for ALS treatment, showing activity in cellular and animal models.

The paper investigates the role of ECM molecules in regulating PNNs, inhibitory interneurons, synaptic distribution, and Otx2 in the visual cortex of knockout mice.

The paper shows APP-CT fragments form nuclear aggregates with PML and FE65 in aged human brains, but not in cerebral organoids, and these aggregates are reduced in Alzheimer's disease regions with high plaque load.