Author

Maia Kinnebrew

Stanford MedicineORCID 0000-0002-7344-8231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Rajat RohatgiiD· 2 shared Alyssa RiglosiD· 1 shared Andres M. LebensohniD· 1 shared Anna I. L. Ostrem· 1 shared Chai-Wan KimiD· 1 shared Chandni B. PateliD· 1 shared Chris E. WilliamsiD· 1 shared Christian SieboldiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

Rajat RohatgiORCID

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3 papers

Recent·Most cited

The E3 ubiquitin ligase MGRN1 targets melanocortin receptors MC1R and MC4R via interactions with transmembrane adapters

Pragya Parashara, Lei Gao, Alyssa Riglos, Dorothy Lartey, Sonia B. Sidhu, Tessa Marks, Chris E. Williams, Grace Siauw, Kai-Jing Lee, Anna I. L. Ostrem, Christian Siebold, Michael E. Riffle, Maia Kinnebrew, Teresa M. Gunn, Jennifer H. Kong

This study identifies ATRN and ATRNL1 as transmembrane adapters that recruit MGRN1 to ubiquitinate and degrade MC1R and MC4R, expanding the known substrate repertoire of MGRN1.

Journal of Cell Science · Nov 3, 2025Peer-reviewedCell Biology

Fatty acid metabolism controls plasma membrane cholesterol accessibility via ATGL-dependent phospholipid remodeling

Kalani M. Wijesinghe, Chai-Wan Kim, Summer Chen, Emily O Schad, Erin Takeshima, Shuo Li, Chandni B. Patel, Dylan Calhoon, Megan Danielewicz, Ryan D. Leib, Javier García‐Bermúdez, Desiree Tillo, Andres M. Lebensohn, James A. Olzmann, Rajat Rohatgi, Maia Kinnebrew

This study shows that fatty acid metabolism regulates plasma membrane cholesterol accessibility through ATGL-dependent phospholipid remodeling, affecting membrane fluidity and cholesterol signaling.

bioRxiv · Aug 21, 2025 · PreprintCell Biology

Multiple modes of cholesterol translocation in the human Smoothened receptor

Prateek D. Bansal, Maia Kinnebrew, Rajat Rohatgi, Diwakar Shukla

The paper investigates cholesterol translocation mechanisms in the Smoothened receptor using simulations and experiments, showing that outer leaflet translocation has a lower energy barrier.

bioRxiv · Nov 25, 2024Biochemistry