Author

Bryn M. Owen

Hammersmith HospitalORCID 0000-0001-5296-7553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:zebrafish· 1

Frequent Co-Authors

Aida Martínez-SáncheziD· 1 shared Alex MontoyaiD· 1 shared Anna G. RobertsiD· 1 shared Aylin Carla HanyalogluiD· 1 shared Ben J. JonesiD· 1 shared Brian LamiD· 1 shared Cecilia Dunsterville· 1 shared Céline Cruciani‐GuglielmacciiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Aida Martínez-SánchezORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis by enhancing GLP-1 secretion and L-cell differentiation

Phyllis Phuah, Mariana Norton, Sijing Cheng, Anna G. Roberts, Leah Meyer, Pei-En Chung, Cecilia Dunsterville, Rafal Karwowski, Brian Lam, Emile Otsubo, Sofia Aleksashina, Fiona Mary Gribble, Frank M. Reimann, Aylin Carla Hanyaloglu, Giles S.H. Yeo, , Kevin G. Murphy

This paper shows indole, a gut microbial metabolite, improves glucose control by boosting GLP-1 secretion and L-cell differentiation in mice, suggesting it could be used as a therapeutic for type 2 diabetes.

bioRxiv · Jun 24, 2025 · PreprintPhysiology

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

Seyedeh Neda Mousavy-Gharavy, Bryn M. Owen, Steven J. Millership, PAULINE L. CHABOSSEAU, Grazia Pizza, Aida Martínez-Sánchez, Emirhan Taşöz, Eleni Georgiadou, Ming Hu, Nicholas H. F. Fine, David Aaron Jacobson, Matthew T. Dickerson, Olof Idevall‐Hagren, Alex Montoya, Holger Kramer, , Guy A. Rutter

This study investigates the role of C2cd4b in murine glucose homeostasis, revealing sexually dimorphic effects on body weight and glucose tolerance.

Diabetologia · Jan 25, 2021Peer-reviewedGenetics