Author

Jocelyn Holkham

Cancer Research UKORCID 0000-0001-5337-1807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alex von KriegsheimiD· 2 shared Simon WilkinsoniD· 2 shared Agata N MakariD· 1 shared Alain J. Kemp· 1 shared Carla Salomo-ColliD· 1 shared Damian J. MoleiD· 1 shared Hywel Dunn-DaviesiD· 1 shared Jennifer P. MortoniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Alex von KriegsheimORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyDevelopmental CellPeer-reviewedAug 15, 2025

Dysproteostasis primes pancreatic epithelial state changes in KRAS-mediated oncogenesis

Carla Salomo-Coll, Marisa Di Monaco, Jocelyn Holkham…·Simon Wilkinson

This study shows that proteostatic failure in ER-phagy, driven by Kras, leads to protein aggregates that prime acinar-ductal metaplasia and pancreatic cancer.

7 citationstop 4%

mouseproteomics

BiochemistryJournal of Proteome ResearchPeer-reviewedJun 19, 2025

Overcoming preservation challenges to enable single-cell proteomics of fixed cell and tissue samples with retained proteome integrity

Agata N Makar, Jocelyn Holkham, Sérgio Lilla…·Alex von Kriegsheim

This paper develops a method to perform single-cell proteomics on preserved tissues, expanding its applicability by overcoming sample preservation challenges.

5 citations

mouseproteomics