Author

Sean E. McGeary

Harvard UniversityORCID 0000-0001-5343-6447Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1 Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Allon Moshe KleiniD· 3 shared Sean G. MegasoniD· 2 shared Alexander O. Subtelny· 1 shared Bianca Lemke· 1 shared Bill JiaiD· 1 shared Bo GuiD· 1 shared David P. BarteliD· 1 shared Dongyang LiiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersDevelopmental Biology

Allon Moshe KleinORCID

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5 papers

Recent·Most cited

Synthetic BiologyMolecular CellPeer-reviewedDec 19, 2025

miRNA modules for precise, tunable control of gene expression

Rongrong Du, Michael J. Flynn, Karan Mahe…·Michael B. Elowitz

The paper introduces DIMMERs, miRNA-based circuits that enable precise, tunable control of transgene expression across cell types, improving gene therapy and research applications.

21 citationstop 4%

mouseexperimental assay

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Cell BiologyBiophysical JournalPeer-reviewedOct 9, 2025

Tissue Fluidity Mediates a Trade-off Between the Speed and Accuracy of Multicellular Patterning by Cell Sorting

Rikki M. Garner, Sean E. McGeary, Allon Moshe Klein, Sean G. Megason

This paper shows that tissue fluidity regulates the speed and accuracy of adhesion-based cell sorting through a trade-off between cell motility and adhesion.

11 citationstop 3%

biophysical modelingcell signaling & trafficking

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Developmental BiologyNature Cell BiologyPeer-reviewedNov 8, 2024

Global decoupling of cell differentiation from cell division in early embryo development

Kalki Kukreja, Bill Jia, Sean E. McGeary…·Allon Moshe Klein

This study shows cell division is dispensable for differentiation of embryonic tissues in zebrafish but affects cell state proportions.

21 citations

zebrafishscRNA-seq

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Developmental BiologyCellPeer-reviewedOct 17, 2023

A mouse model with high clonal barcode diversity for joint lineage, transcriptomic, and epigenomic profiling in single cells

Li Li, Sarah Bowling, Sean E. McGeary…·Fernando D. Camargo

167 citationstop 1%

mousescRNA-seq

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GenomicsMolecular CellPeer-reviewedJan 2, 2020

The Dynamics of Cytoplasmic mRNA Metabolism

Timothy J. Eisen, Stephen W. Eichhorn, Alexander O. Subtelny…·David P. Bartel

The paper examines mRNA metabolism dynamics in mouse fibroblasts, finding that deadenylation rates determine cytoplasmic mRNA stability and degradation.

178 citationstop 2%

mousebulk RNA-seq

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