M. Zuhaib Qayyum

This study investigates how ion species and milling voltage affect cryo-pFIB-SEM image quality, showing that optimal settings depend on specimen composition.

The paper analyzes depth-dependent structural damage caused by cryo-FIB milling using apoferritin as a reporter, showing damage varies with ion type and molecular target.

This study presents the structure of Si3, a unique insertion in cyanobacterial RNA polymerase, and shows it does not affect catalytic activity despite large motion.

This paper reveals the structural mechanism of NusG-dependent transcription pausing by showing how NusG interacts with the TTNTTT motif to inhibit RNAP conformational changes required for RNA synthesis.

This study reveals how DksA/ppGpp regulates rRNA transcription by altering RNAP conformation and promoter DNA binding in Escherichia coli.

The paper determines the cryo-EM structure of E. coli σ70 RNAP and promoter DNA complex, revealing a role of σNCR in open complex formation.