Eric Perlman

The paper presents the first densely reconstructed adult fruit fly connectome integrating the brain and ventral nerve cord, revealing distributed control circuits involving local and long-range neural connections.

The paper characterizes the 3D organization of large axons in human white matter, revealing distinct architectural patterns across different brain regions.

The paper presents the first neuronal wiring diagram of a whole adult Drosophila brain, revealing synaptic connections and circuit mechanisms underlying sensorimotor behaviors.

The paper introduces a computational pipeline for automated tracing and assembly of axons across serial sections, validated on centimeter-scale data for orientation analysis and proofreading.

The paper visualizes dense distributions of immunolabeled proteins in adult macaque visual cortex using expansion microscopy and light sheet imaging, enabling multimodal atlas creation.

Annotating the 127,978-neuron FlyWire fly connectome yields 4,552 cell types, 3,094 cross-validated against the hemibrain; cell-type edges above 10 synapses or 1.1% of input recur over 90% across hemispheres.

The paper presents a scalable pipeline for assembling large electron microscopy datasets into 3D volumes, achieving high throughput and modular design for efficient processing.

The paper maps PN-to-KC connections in Drosophila MB using EM and shows connectivity biases that enhance discrimination of food-related odor combinations.

Flood-filling networks with local section realignment segment a forty-teravoxel whole-brain Drosophila electron microscopy volume, making circuit reconstruction an order of magnitude faster than manual tracing.

The paper provides a complete electron microscopy volume of the adult Drosophila melanogaster brain, revealing new insights into synaptic connectivity and neuronal circuitry.