Feng Li

Sexual dimorphism in the complete connectome of the Drosophila male central nervous system

The paper presents the complete connectome of the Drosophila male central nervous system and compares it to the female connectome, identifying sex-specific and dimorphic neuronal types.

A Connectome of the Male Drosophila Ventral Nerve Cord

Roughly 23 thousand traced neurons and 10 million TBars of the male Drosophila nerve cord, reconstructed from electron microscopy, typed, and queryable in neuPrint down to motor neurons.

Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation

The paper systematically annotates a complete adult male Drosophila nerve cord connectome, identifying neuron types, connectivity patterns, and sensory modalities to reveal organizational principles.

The connectome of an insect brain

The paper maps the synaptic-resolution connectome of a Drosophila larva brain, identifying neuron types, circuit motifs, and structural features.

Hierarchical architecture of dopaminergic circuits enables second-order conditioning in Drosophila

The paper identifies a feedforward circuit between dopamine subsystems in Drosophila that is essential for second-order conditioning, mediated by a key interneuron.

Structured sampling of olfactory input by the fly mushroom body

The paper maps PN-to-KC connections in Drosophila MB using EM and shows connectivity biases that enhance discrimination of food-related odor combinations.

Information flow, cell types and stereotypy in a full olfactory connectome

The paper describes the Drosophila olfactory system using a connectome, identifies information flow patterns, and quantifies stereotypy across individuals.

Automated Reconstruction of a Serial-Section EM Drosophila Brain with Flood-Filling Networks and Local Realignment

Flood-filling networks with local section realignment segment a forty-teravoxel whole-brain Drosophila electron microscopy volume, making circuit reconstruction an order of magnitude faster than manual tracing.

A Connectome and Analysis of the Adult Drosophila Central Brain

The paper presents a detailed connectome of the adult Drosophila central brain, including new methods for data analysis and biological insights into neural circuit organization.

The connectome of the adult Drosophila mushroom body: implications for function

The paper maps the synaptic connectivity of the Drosophila mushroom body and identifies new circuit components and structures in sensory input processing and output modulation.

Complete connectomic reconstruction of olfactory projection neurons in the fly brain

The paper reconstructs the complete connectome of olfactory projection neurons in the Drosophila brain and identifies new connectivity patterns in olfactory circuits.

Input connectivity reveals additional heterogeneity of dopaminergic reinforcement in Drosophila

The paper identifies anatomical subtypes of dopaminergic neurons in Drosophila and their specific input connectivity, revealing functional roles in reinforcement and memory.

Connectomics analysis reveals first, second, and third order thermosensory and hygrosensory neurons in the adult Drosophila brain

The paper identifies new thermosensory and hygrosensory glomeruli and neurons in the Drosophila brain using connectomics, revealing their connections to higher brain centers and circadian clock circuits.

A Connectome of the Adult Drosophila Central Brain

A dense electron-microscopy reconstruction of half the fly central brain, with nearly every cell typed and queryable online, turns months of tracing partners into a database lookup.

Regulation of modulatory cell activity across olfactory structures in Drosophila melanogaster

The paper investigates how a serotonergic modulatory neuron in Drosophila integrates and responds differently in distinct olfactory neuropils, showing local regulation of transmitter release.

The Feeding Connectome: Convergence of Monosynaptic and Polysynaptic Sensory Paths onto Common Motor Outputs

The paper maps sensory input pathways and their connections to motor outputs in Drosophila larvae, revealing monosynaptic and polysynaptic routes that converge on common motor targets.

Neurogenetic dissection of the Drosophila innate olfactory processing center

The paper generates split-GAL4 driver lines to map and functionally characterize 82 cell types in the Drosophila lateral horn, revealing connectivity with mushroom bodies and identifying cell types that influence behavior.

The Complete Connectome Of A Learning And Memory Center In An Insect Brain

The paper reconstructs the complete synaptic connectome of the Drosophila larval mushroom body, revealing novel circuit structures and input integration patterns in Kenyon cells.

Synaptic Transmission Parallels Neuromodulation in a Central Food-Intake Circuit

The paper identifies acetylcholine and hugin neuropeptide as necessary for feeding regulation in Drosophila, showing parallels with neuromedinU in mammals.

The wiring diagram of a glomerular olfactory system

The paper maps the complete wiring diagram of the Drosophila larval antennal lobe, revealing two parallel circuits involving projection neurons and local neurons that process olfactory signals.

Quantitative neuroanatomy for connectomics in Drosophila

The paper introduces methods to improve neuronal circuit reconstruction in Drosophila by leveraging anatomical features and synaptic connectivity patterns to reduce reconstruction errors.