Davi D. Bock

The paper maps synapse types across the Drosophila brain connectome, revealing structured patterns of mixed polarity and reciprocal connectivity.

The paper presents the first neuronal wiring diagram of a whole adult Drosophila brain, revealing synaptic connections and circuit mechanisms underlying sensorimotor behaviors.

The paper describes an automated ultra-microtome for TEM sectioning, achieving high success rates in cutting and picking up sections from various biological samples.

The paper reconstructs and identifies 58 Lobula Plate Tangential Neurons in Drosophila using EM and predicts their optic flow sensitivity through computational anatomy.

The paper identifies a competitive disinhibitory network in Drosophila that enhances rotational optic flow processing for navigation.

Annotating the 127,978-neuron FlyWire fly connectome yields 4,552 cell types, 3,094 cross-validated against the hemibrain; cell-type edges above 10 synapses or 1.1% of input recur over 90% across hemispheres.

The paper shows that the preferred directions of Drosophila DS neurons are shaped by the compound eye's structure, linking peripheral anatomy to neural function and behavior.

The paper maps PN-to-KC connections in Drosophila MB using EM and shows connectivity biases that enhance discrimination of food-related odor combinations.

The paper reconstructs gustatory projections in Drosophila melanogaster brains to show taste modality segregation and synaptic connectivity patterns.

The paper maps synaptic targets of color and polarization-sensitive photoreceptors in Drosophila, revealing modality-specific wiring and spatial segregation in neural circuits.

This study shows that memory consolidation in Drosophila involves structural and functional reorganization of a specific neural circuit in the mushroom body.

The paper investigates how spatial information is processed in a Drosophila glomerulus lacking retinotopy, finding that connectivity preserves spatial readout of visual looming.

Geosmin avoidance in Drosophila runs from a labelled line at the periphery into a distributed central representation spanning 80 third-order cell types, then into specific descending neurons.

Flood-filling networks with local section realignment segment a forty-teravoxel whole-brain Drosophila electron microscopy volume, making circuit reconstruction an order of magnitude faster than manual tracing.

This study identifies the neural network structure of the Drosophila heading direction system, confirming it contains ring attractor components and revealing novel structural features.

The paper maps the connectivity of a serotonergic neuron in Drosophila, showing its distinct wiring patterns in different olfactory regions and interactions with local networks.

The paper reconstructs the complete connectome of olfactory projection neurons in the Drosophila brain and identifies new connectivity patterns in olfactory circuits.

The paper identifies anatomical subtypes of dopaminergic neurons in Drosophila and their specific input connectivity, revealing functional roles in reinforcement and memory.

The paper identifies new thermosensory and hygrosensory glomeruli and neurons in the Drosophila brain using connectomics, revealing their connections to higher brain centers and circadian clock circuits.

The paper identifies distinct mechanosensory neuron subpopulations in Drosophila that converge onto a shared neural circuit to elicit grooming behavior.

The paper presents an automatic method to identify synaptic partners in a whole-brain Drosophila EM dataset using convolutional neural networks, achieving high accuracy in predicting synaptic connections.

The paper shows that hungry Drosophila use a neural circuit involving dopamine and octopamine to balance perseverance and withdrawal during food seeking.

The paper identifies 165 cell types in the Drosophila lateral horn and shows that 33 of them have stereotyped odor responses, revealing principles of odor categorization in a higher olfactory center.

The paper investigates how a serotonergic modulatory neuron in Drosophila integrates and responds differently in distinct olfactory neuropils, showing local regulation of transmitter release.

The paper identifies two LH cell-types in Drosophila that are required for aversive memory retrieval and show that memory information is passed from the mushroom body to the lateral horn.

The paper generates split-GAL4 driver lines to map and functionally characterize 82 cell types in the Drosophila lateral horn, revealing connectivity with mushroom bodies and identifying cell types that influence behavior.

The paper provides a complete electron microscopy volume of the adult Drosophila melanogaster brain, revealing new insights into synaptic connectivity and neuronal circuitry.