Zeguo Sun

This study identifies a T-cell intrinsic mechanism by which APOL1 risk alleles contribute to kidney rejection through altered calcium signaling and T-cell activation.

This study identifies the Shroom3 ASD2-domain as critical for profibrotic function in CKD through ROCK activation, showing motif-specific roles in renal fibrosis and albuminuria.

The paper identifies four SNPs in the LILRB3 gene associated with graft failure in African American kidney transplant recipients and links them to immune-related diseases.

This paper develops a deep-learning model to assess kidney biopsy images, predicting graft loss and guiding organ utilization by improving upon traditional scoring methods.