Author

Zhengzi Yi

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Weijia ZhangiD· 4 shared Lorenzo G. GalloniD· 3 shared Madhav C. MenoniD· 3 shared Robert B. ColviniD· 3 shared Zeguo SuniD· 3 shared Caixia XiiD· 2 shared Chengguo WeiiD· 2 shared Cijiang HeiD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Weijia ZhangORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Early developmental placental defects and pregnancy loss in lupus mice expressing human TLR8

Naomi I. Maria, Yunwei Xia, Chirag Raparia, Ke Lin, Shani Martinez, Zhengzi Yi, Weijia Zhang, Monowar Aziz, Ping Wang, Marta M. Guerra, Jane E. Salmon, Jenny L. Sones, Arnon Arazi, Paul Hoover, Anne Davidson

This study identifies huTLR8's role in placental defects and pregnancy loss in lupus mice, showing its involvement in immune dysregulation and inflammation.

bioRxiv · Feb 9, 2026 · PreprintImmunology

Genetic polymorphisms of Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3) gene in African American kidney transplant recipients are associated with post-transplant graft failure

Zeguo Sun, Zhengzi Yi, Chengguo Wei, Wenlin Wang, Paolo Cravedi, Fasika M. Tedla, Stephen C. Ward, Evren U. Azeloglu, Daniel R. Schrider, Yun Li, Sumaria Ali, Tianyuan Ren, Shun Liu, Deguang Liang, Jia Fu, , Weijia Zhang

The paper identifies four SNPs in the LILRB3 gene associated with graft failure in African American kidney transplant recipients and links them to immune-related diseases.

bioRxiv · Feb 21, 2024 · PreprintGenetics

Deep-learning Based Pathological Assessment of Frozen Procurement Kidney Biopsies Predicts Graft Loss and Guides Organ Utilization: A Large-scale Retrospective Study

Zhengzi Yi, Caixia Xi, Madhav C. Menon, Paolo Cravedi, Fasika M. Tedla, Alan Soto, Zeguo Sun, Keyu Liu, Jason Zhang, Chengguo Wei, Man Chen, Wenlin Wang, Brandon M. Veremis, Mónica Garcı́a-Barros, Abhishek Kumar, , Weijia Zhang

This paper develops a deep-learning model to assess kidney biopsy images, predicting graft loss and guiding organ utilization by improving upon traditional scoring methods.

bioRxiv · May 31, 2023 · PreprintBioinformatics

Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 locus mismatches associated with long-term renal transplant survival

Zeguo Sun, Zhongyang Zhang, Khadija Banu, Ian W. Gibson, Robert B. Colvin, Zhengzi Yi, Weijia Zhang, Bony De Kumar, John F. Pell, Arjang Djamali, Lorenzo G. Gallon, Philip J. O’Connell, Cijiang He, Jordan S. Pober, Peter S. Heeger, Madhav C. Menon

bioRxiv · Dec 21, 2022 · PreprintGenetics