Author

John F. Pell

Yale UniversityORCID 0009-0000-9641-2445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Cijiang HeiD· 3 shared Madhav C. MenoniD· 3 shared Zhengliang SuniD· 3 shared Anand Chellappan ReghuvaraniD· 2 shared Bony De KumariD· 2 shared E. M. TanviriD· 2 shared Gabriel BarsottiiD· 2 shared Hongmei ShiiD· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Cijiang HeORCID

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3 papers

Recent·Most cited

ImmunologyAmerican Journal of TransplantationPeer-reviewedAug 1, 2025

A T-cell Intrinsic Role for APOL1 Risk Alleles in Allograft Rejection

John F. Pell, E. M. Tanvir, Zhengliang Sun…·Madhav C. Menon

This study identifies a T-cell intrinsic mechanism by which APOL1 risk alleles contribute to kidney rejection through altered calcium signaling and T-cell activation.

DOI 10.1016/j.ajt.2025.07.188

mousebulk RNA-seq

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Systems BiologybioRxivPreprintNov 22, 2024

Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allele.

Anand Chellappan Reghuvaran, Ashwani Kumar, Qisheng Lin…·Madhav C. Menon

This study identifies the Shroom3 ASD2-domain as critical for profibrotic function in CKD through ROCK activation, showing motif-specific roles in renal fibrosis and albuminuria.

2 citations

mousebulk RNA-seq

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GeneticsbioRxivPreprintDec 21, 2022

Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 locus mismatches associated with long-term renal transplant survival

Zeguo Sun, Zhongyang Zhang, Khadija Banu…·Madhav C. Menon

1 citation

humanwhole-genome sequencing

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