Lorenzo G. Gallon

Evaluation of Methodologies in Anti-nephrin Autoantibody Detection

The paper evaluates different methodologies for detecting anti-nephrin autoantibodies and finds that combined methods yield the most reliable results, with only two positive cases identified among 127 samples.

Cellular and Molecular Resolution of Focal Segmental Glomerulosclerosis Recurrence in Human Allografts

This study uses snRNA-seq to analyze kidney transplant biopsies and identifies molecular and cellular mechanisms of recurrent FSGS, including podocyte loss and PEC dedifferentiation.

Genetic polymorphisms of Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3) gene in African American kidney transplant recipients are associated with post-transplant graft failure

The paper identifies four SNPs in the LILRB3 gene associated with graft failure in African American kidney transplant recipients and links them to immune-related diseases.

Deep-learning Based Pathological Assessment of Frozen Procurement Kidney Biopsies Predicts Graft Loss and Guides Organ Utilization: A Large-scale Retrospective Study

This paper develops a deep-learning model to assess kidney biopsy images, predicting graft loss and guiding organ utilization by improving upon traditional scoring methods.

Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 locus mismatches associated with long-term renal transplant survival