Meena Sukhwani

The paper validates three TEX11 variants associated with human azoospermia by generating mouse models and observing fertility and spermatogenesis defects.

This study uses single-cell RNA-seq to analyze age-related changes in human testis and finds that dysregulation correlates with BMI in older men.

This study identifies Tcf21+ mesenchymal progenitors in mouse testis that contribute to somatic cell development, homeostasis, and regeneration.

The paper uses single-cell RNA sequencing to compare spermatogenesis in human, macaque, and mouse testes, identifying conserved and divergent molecular features across species.

This study validates the differentiation of rhesus macaque primordial germ cell-like cells (rPGCLCs) using transplantation into adult gonadal niches, showing they commit to late PGCs and spermatogonia-like cells but not ENO2-positive spermatogonia.