NeuroscienceActa NeuropathologicaPeer-reviewed
Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region
Tomáš Ondrejčák, Neng‐Wei Hu, Emily Coode…·Igor V. Klyubin
This study shows that extracellular tau's synaptotoxic effects are mediated by its microtubule-binding region, and targeting this region can reverse synaptic plasticity disruption.
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