Author

Grant T. Corbett

Brigham and Women's HospitalORCID 0000-0003-3606-9686Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Dominic M. WalshiD· 2 shared Arturo J. MorenoiD· 1 shared Emily Coode· 1 shared Frederick J. LiveseyiD· 1 shared Igor V. KlyubiniD· 1 shared Inna SlutskyiD· 1 shared Ivan DoykoviD· 1 shared Kevin A. MillsiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Dominic M. WalshORCID

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2 papers

Recent·Most cited

Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region

Tomáš Ondrejčák, Neng‐Wei Hu, Emily Coode, Tom Campbell, Grant T. Corbett, Ivan Doykov, Kevin A. Mills, Dominic M. Walsh, Frederick J. Livesey, Michael J. Rowan, Igor V. Klyubin

This study shows that extracellular tau's synaptotoxic effects are mediated by its microtubule-binding region, and targeting this region can reverse synaptic plasticity disruption.

Acta Neuropathologica · Jun 2, 2025Peer-reviewedNeuroscience

Human brain-derived Aβ oligomers bind to synapses and disrupt synaptic activity in a manner that requires APP

Zemin Wang, Rosemary J. Jackson, Wei Hong, Walter M. Taylor, Grant T. Corbett, Arturo J. Moreno, Wen Liu, Shaomin Li, Matthew P. Frosch, Inna Slutsky, Tracy L. Young‐Pearse, Tara L. Spires‐Jones, Dominic M. Walsh

The paper shows that Aβ oligomers from AD brain bind to synapses and disrupt synaptic activity, and this requires APP.

Journal of Neuroscience · Nov 3, 2017Peer-reviewedNeuroscience