Author

Ailing Lu

Feinstein Institute for Medical ResearchORCID 0000-0001-5572-7790Unclaimed ORCID profile · follow to get notified of new preprints

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Amanda HuangiD· 3 shared Betsy Jo BarnesiD· 3 shared Jessica A. HamermaniD· 2 shared Allison R. O’Rourke· 1 shared Bharati MattaiD· 1 shared Carmen R. MikaceniciD· 1 shared Cate SpeakeiD· 1 shared Daniel CampbelliD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersImmunology

Amanda HuangORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 16, 2026

Myeloid IRF5 is required for TLR7-driven inflammatory hemophagocyte differentiation and Macrophage Activation Syndrome

Natalie K. Thulin, Ailing Lu, Susana L. Orozco…·Betsy Jo Barnes

This study identifies IRF5 as a critical driver of iHPC differentiation and MAS pathogenesis, showing it can be targeted pharmacologically.

DOI 10.64898/2026.08.18.745337

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 23, 2026

Type I Interferon-Driven Monocyte Dysregulation and MAS-associated CD8+ T cells During Macrophage Activation Syndrome

Susan Canny, Hannah A. DeBerg, Emma Lo Kuan…·Jessica A. Hamerman

The paper identifies a type I IFN-driven monocyte dysregulation and a MAS-associated CD8+ T cell population in macrophage activation syndrome using bulk and single-cell RNA sequencing.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 26, 2024

IRF5 mediates adaptive immunity via altered glutamine metabolism, mTORC1 signaling and post-transcriptional regulation following T cell receptor activation

Zarina Brune, Ailing Lu, Matthew A. Moss…·Betsy Jo Barnes

This study identifies IRF5 as a key regulator of T cell effector function through mTORC1 signaling, glutamine metabolism, and post-transcriptional control following TCR activation.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky