Author

Xiaojie Yu

Hong Kong University of Science and TechnologyORCID 0000-0001-5586-0428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aatish ThennavaniD· 1 shared Abhishek KoladiyaiD· 1 shared Anuj K. Peri· 1 shared Bo LviD· 1 shared Bokai ZhuiD· 1 shared David Z. Z. HeiD· 1 shared Fangling Tian· 1 shared Guillermina LozanoiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

Aatish ThennavanORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 14, 2026

Trp53 heterozygosity defines novel states impacting tumor plasticity and progression in Kras-initiated non-small cell lung cancer

V Mitheera, Abhishek Koladiya, Aatish Thennavan…·Guillermina Lozano

This study shows that TP53 heterozygosity in Kras-mutant lung cancer affects tumor plasticity and progression, with distinct genomic and survival outcomes compared to complete TP53 loss.

DOI 10.64898/2026.10.12.758643

mousescRNA-seq

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Cell BiologybioRxivPreprintJul 9, 2026

SOLAR Mediates Lysosomal Membrane Repair and Redox Defense

Jinrui Xun, Zhenjie Yi, H Y Yang…·Jay Xiaojun Tan

This study identifies SOLAR as a lysosomal quality control pathway that links CASM to p62-driven membrane repair and redox signaling, with implications for aging and degenerative disease.

1 citation

humanproteomics

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NeuroscienceiSciencePeer-reviewedMar 31, 2023

Apicosome: newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cells

Xiaofen Li, Qirui Zhao, Xiaojie Yu…·Pingbo Huang

The paper identifies a new organelle, the apicosome, specific to mouse cochlear and vestibular hair cells and describes its developmental dynamics and potential functional roles.

DOI 10.1016/j.isci.2023.106535

mouseexperimental assay

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