Author

Bo Lv

University of PittsburghORCID 0000-0002-3448-8986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Jay Xiaojun TaniD· 2 shared Anuj K. Peri· 1 shared Bing Hu· 1 shared Bokai ZhuiD· 1 shared Chun LiiD· 1 shared Fangling Tian· 1 shared Fanze Meng· 1 shared Fenghe DuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

Jay Xiaojun TanORCID

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3 papers

Recent·Most cited

Evolutionary Origins and Synthetic Reconstruction of Gingerols

Weihao Wang, Qingmin Li, Jun Zhang, Xiaosong Yu, Xinyi Li, Fanze Meng, Haiyang Jia, Bing Hu, Bo Lv, Lei Qin, Chun Li

The paper identifies the evolutionary origins and reconstructs the biosynthetic pathway of gingerols using multi-omics approaches, enabling microbial production of 6-gingerol.

bioRxiv · Jul 30, 2026 · PreprintSynthetic Biology

SOLAR Mediates Lysosomal Membrane Repair and Redox Defense

Jinrui Xun, Zhenjie Yi, H Y Yang, Jenny Cheng, William A. Dion, Rae Yang, Xiaojie Yu, Fangling Tian, Bo Lv, Henry F. Liu, Anuj K. Peri, Bokai Zhu, Jay Xiaojun Tan

This study identifies SOLAR as a lysosomal quality control pathway that links CASM to p62-driven membrane repair and redox signaling, with implications for aging and degenerative disease.

bioRxiv · Jul 9, 2026 · PreprintCell Biology

PtdIns(3,5)P2 Is an Endogenous Ligand of STING in Innate Immune Signaling

Jay Xiaojun Tan, Bo Lv, Jie Li, Tuo Li, Fenghe Du, Xiang Chen, Xuewu Zhang, Xiao-Chen Bai, Zhijian J. Chen

This study identifies PtdIns(3,5)P2 as an endogenous ligand of STING that cooperates with cGAMP to activate innate immune signaling.

bioRxiv · Dec 29, 2025 · PreprintBiochemistry