Author

Maria A Prostova

Russian Academy of SciencesORCID 0000-0001-5630-3471Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Assay:DNA methylation· 3 Approach:experimental assay· 3 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andrey V. KulbachinskiyiD· 3 shared Daria EsyuninaiD· 3 shared Vladimir PanteleeviD· 3 shared Alexei A. AraviniD· 2 shared Lidiya LisitskayaiD· 2 shared Aleksei AgapoviD· 1 shared Anastasiia OkhtienkoiD· 1 shared Anna KanevskayaiD· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMolecular Biology

Andrey V. KulbachinskiyORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 8, 2023

DNA-targeting short Argonaute triggers effector nuclease to protect bacteria from invaders

Maria A Prostova, Anna Kanevskaya, Vladimir Panteleev…·Andrey V. Kulbachinskiy

The paper shows that NbaAgo forms a complex with an effector nuclease to cleave DNA/RNA upon target recognition, providing bacterial immunity against invaders.

2 citations

bacteria (other)DNA methylation

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedApr 24, 2023

Bacterial Argonaute nucleases reveal different modes of DNA targeting in vitro and in vivo

Lidiya Lisitskaya, Ekaterina Kropocheva, Aleksei Agapov…·Andrey V. Kulbachinskiy

This study investigates the DNA targeting mechanisms of five bacterial Argonaute proteins in vitro and in vivo, revealing their ability to cleave DNA and defend against bacteriophages.

26 citations

bacteria (other)DNA methylation

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedMar 23, 2023

Specific targeting of plasmids with Argonaute enables genome editing

Daria Esyunina, Anastasiia Okhtienko, Anna Olina…·Andrey V. Kulbachinskiy

This paper demonstrates that CbAgo from Clostridium butyricum can be used for targeted genomic DNA cleavage and recombineering by using plasmid-derived gDNAs.

39 citations

bacteria (other)DNA methylation

𝕏 PostBluesky