Loss of restriction-modification methyltransferases drives persistence to fluoroquinolones in Pseudomonas aeruginosa
Maureen Micaletto, Nicolas Oswaldo Gomez, Anna Olina…·Stefano Pagliara
This study shows that loss of type I restriction-modification methyltransferases in Pseudomonas aeruginosa increases fluoroquinolone persistence through enhanced SOS response and slower growth.