Daria Esyunina

The paper shows that NbaAgo forms a complex with an effector nuclease to cleave DNA/RNA upon target recognition, providing bacterial immunity against invaders.

This study investigates the DNA targeting mechanisms of five bacterial Argonaute proteins in vitro and in vivo, revealing their ability to cleave DNA and defend against bacteriophages.

This paper demonstrates that CbAgo from Clostridium butyricum can be used for targeted genomic DNA cleavage and recombineering by using plasmid-derived gDNAs.

This paper describes a programmable pAgo nuclease from Kurthia massiliensis that can cleave both DNA and RNA targets with guide flexibility and mismatch sensitivity.

This study reveals how DksA/ppGpp regulates rRNA transcription by altering RNAP conformation and promoter DNA binding in Escherichia coli.

This study shows that the bacterial Argonaute nuclease CbAgo uses DNA interference to cleave multicopy genetic elements like plasmids and transposons by generating small DNA guides through cooperation with repair machinery.