Author

Jingjing Shi

Chinese Academy of SciencesORCID 0000-0001-5640-8687Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Erli You· 2 shared H. Eric XuiD· 2 shared Hualiang JiangiD· 2 shared Shuyang ZhangiD· 2 shared Wanchao YiniD· 2 shared Xiaodong LuaniD· 2 shared Yi JiangiD· 2 shared Chunyou MaoiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMolecular Biology

Erli You

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 3, 2021

Structures of full-length glycoprotein hormone receptor signaling complexes

Jia Duan, Peiyu Xu, Xi Cheng…·H. Eric Xu

The paper reports cryo-EM structures of LHCGR in different activation states, revealing a push and pull mechanism of receptor activation and the role of an allosteric agonist.

DOI 10.1101/2021.08.03.454894

humanprotein structure

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 6, 2020

Structural basis for repurposing a 100-years-old drug suramin for treating COVID-19

Wanchao Yin, Xiaodong Luan, Zhihai Li…·H. Eric Xu

The paper discovers suramin as a potent inhibitor of SARS-CoV-2 RNA polymerase and provides its structural mechanism for repurposing in treating COVID-19.

5 citations

experimental assaydrug response / drug discovery

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