Author

Samantha E. Spellicy

Duke UniversityORCID 0000-0001-5648-8816Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adam SchwartziD· 1 shared Aditya A MohaniD· 1 shared Anoop P. PateliD· 1 shared Ariel T Gonzalez· 1 shared Bhairavy J. PuviindraniD· 1 shared Carter M. SuryadevaraiD· 1 shared Daniel Wilkinson· 1 shared Eliese MoelkeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adam SchwartzORCID

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1 paper

Recent·Most cited

ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedMar 1, 2026

IL-12 Secreting CAR-T Cells Reprogram the Tumor Microenvironment and Improve Efficacy Against Heterogeneous Models of Glioblastoma

Steven Shen, Aditya A Mohan, Kelly M. Hotchkiss…·Anoop P. Patel

This study shows that IL-12-secreting CAR-T cells improve glioblastoma treatment by enhancing T-cell persistence and reprogramming the tumor microenvironment without lymphodepletion.

4 citationstop 2%

mouseexperimental assay

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