Author

Aditya A Mohan

Duke UniversityORCID 0000-0001-7614-9387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Anoop P. PateliD· 2 shared Katayoun AyasoufiiD· 2 shared Kelly M. HotchkissiD· 2 shared Peter Edward FecciiD· 2 shared Sarah L. CookiD· 2 shared Adam SchwartziD· 1 shared Alexandra M. Hoyt-MiggelbrinkiD· 1 shared Andrew A. HardiganiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Anoop P. PatelORCID

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2 papers

Recent·Most cited

ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedMar 1, 2026

IL-12 Secreting CAR-T Cells Reprogram the Tumor Microenvironment and Improve Efficacy Against Heterogeneous Models of Glioblastoma

Steven Shen, Aditya A Mohan, Kelly M. Hotchkiss…·Anoop P. Patel

This study shows that IL-12-secreting CAR-T cells improve glioblastoma treatment by enhancing T-cell persistence and reprogramming the tumor microenvironment without lymphodepletion.

4 citationstop 2%

mouseexperimental assay

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ImmunologyClinical Cancer ResearchPeer-reviewedNov 21, 2025

Upregulation of TNFR2 Precedes TOX Expression by Exhausted T cells and Restricts Antitumor and Antiviral Immunity

Alexandra M. Hoyt-Miggelbrink, Jessica Waibl Polania, Lucas P. Wachsmuth…·Peter Edward Fecci

6 citations

mousebulk RNA-seq

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