Author

Bhairavy J. Puviindran

Duke Medical CenterORCID 0000-0002-8827-0050Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Eliese MoelkeriD· 2 shared John Howard SampsoniD· 2 shared Katayoun AyasoufiiD· 2 shared Kelly M. HotchkissiD· 2 shared Peter Edward FecciiD· 2 shared Sarah L. CookiD· 2 shared Adam SchwartziD· 1 shared Aditya A MohaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Eliese MoelkerORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedMar 1, 2026

IL-12 Secreting CAR-T Cells Reprogram the Tumor Microenvironment and Improve Efficacy Against Heterogeneous Models of Glioblastoma

Steven Shen, Aditya A Mohan, Kelly M. Hotchkiss…·Anoop P. Patel

This study shows that IL-12-secreting CAR-T cells improve glioblastoma treatment by enhancing T-cell persistence and reprogramming the tumor microenvironment without lymphodepletion.

4 citationstop 2%

mouseexperimental assay

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Cancer BiologyJournal of Clinical InvestigationPeer-reviewedApr 17, 2025

IL-7-mediated expansion of autologous lymphocytes increases CD8+ VLA-4 expression and accumulation in glioblastoma models

Kirit Singh, Kelly M. Hotchkiss, Sarah L. Cook…·Peter Edward Fecci

This study shows that IL-7-expanded autologous lymphocytes increase VLA-4 expression and accumulate in glioblastoma tumors, enhancing the effectiveness of T cell-based therapies.

9 citations

mousehuman

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