Madeline H. Cooper

This study shows FGF signaling induces disease-associated oligodendrocyte states and causes myelin pathology in both in vitro and in vivo models.

This study shows actin disassembly enables myelin compaction and wrapping in the CNS by developing live-cell assays and genetic perturbations.

This paper develops nanobodies against CNPase, showing distinct epitopes and functional applications in imaging and as intrabodies.

This study shows that calcium signaling in oligodendrocytes is critical for shaping myelin sheath morphology during myelination in the developing mouse CNS.

This study identifies VAMP2/3-mediated exocytosis as essential for CNS myelin membrane expansion, revealing a pathway critical for myelin formation and potential therapeutic targeting.