FGF signaling induces disease-associated oligodendrocyte states and drives myelin pathology
Maya K. Weigel, Madeline H. Cooper, Mattia Zaghi, Jayakrishnan Gopakumar, Caldwell M. Bridges, Peggy P. Ho, Michael Schoof, Ugne Klibaite, Stacey Pedraza, Eneritz Agirre, George Tilton-Low, Nadine Bestard-Cuche, Petra Kukanja, Veronika V. Rodriguez, Graham Jones, , J. Bradley Zuchero
This study shows FGF signaling induces disease-associated oligodendrocyte states and causes myelin pathology in both in vitro and in vivo models.
bioRxiv · Nov 4, 2026 · PreprintNeuroscience