Author

Lynette B. Naler

Virginia TechORCID 0000-0002-1336-3236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:ChIP-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

Chang LuiD· 4 shared Bohan ZhuiD· 3 shared Zirui ZhouiD· 3 shared Chengyu DengiD· 2 shared Zhengzhi LiuiD· 2 shared Alexander Murray· 1 shared Christopher A. GuevaraiD· 1 shared Danfeng Daphne YaoiD· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenomics

Chang LuORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Epigenomic tomography for probing spatially-defined molecular state in the brain

Zhengzhi Liu, Chengyu Deng, Zirui Zhou, Ya Xiao, Shan Jiang, Bohan Zhu, Lynette B. Naler, Xiaoting Jia, Danfeng Daphne Yao, Chang Lu

This paper introduces a method to map spatial epigenomic variations in brain tissue at a centimeter scale, revealing dynamic changes in specific brain regions due to seizures.

bioRxiv · Nov 24, 2022 · PreprintGenomics

Cell-type-specific epigenomic variations associated with BRCA1 mutation in pre-cancer human breast tissues

Yuan-Pang Hsieh, Lynette B. Naler, Sai Ma, Chang Lu

The paper identifies cell-type-specific epigenomic differences in pre-cancerous breast tissues of BRCA1 mutation carriers compared to non-carriers.

NAR Genomics and Bioinformatics · Jan 13, 2022Peer-reviewedGenomics

Native MOWChIP-seq: Genome-wide profiles of key protein bindings reveal functional differences among various brain regions

Zhengzhi Liu, Lynette B. Naler, Yan Zhu, Chengyu Deng, Qiang Zhang, Bohan Zhu, Zirui Zhou, Mimosa Sarma, Alexander Murray, Hehuang Xie, Chang Lu

The paper introduces native MOWChIP-seq, a low-input ChIP-seq method, and applies it to study protein binding differences between mouse brain regions.

bioRxiv · Jul 11, 2021 · PreprintGenomics

Prolonged epigenetic and synaptic plasticity alterations following single exposure to a psychedelic in mice

Mario de la Fuente Revenga, Bohan Zhu, Christopher A. Guevara, Lynette B. Naler, Justin M. Saunders, Zirui Zhou, Rudy Toneatti, Salvador Sierra, Jennifer T. Wolstenholme, Patrick M. Beardsley, George W. Huntley, Chang Lu, Javier González‐Maeso

This study shows that a single dose of the psychedelic DOI causes long-lasting epigenetic and synaptic changes in mice, linked to antidepressant effects and potential risks for psychiatric disorders.

bioRxiv · Feb 24, 2021 · PreprintNeuroscience