Author

Pei Xin Lim

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-5742-3539Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Maria JasiniD· 2 shared Brett TayloriD· 1 shared Emilie C. B. Desclos· 1 shared Fabio VanoliiD· 1 shared Florian MoratiiD· 1 shared Hayley L. ReiniD· 1 shared Jean GautieriD· 1 shared Jennifer Zagelbaum· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Maria JasinORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedJan 19, 2024

BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair

Pei Xin Lim, Mahdia Zaman, Weiran Feng, Maria Jasin

The paper shows BRCA2 stabilizes RAD51 filaments for fork protection and gap suppression, but HDR deficiency primarily drives chemotherapeutic sensitivity.

77 citationstop 1%

mousehuman

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Molecular BiologyNature CommunicationsPeer-reviewedJul 12, 2021

Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex

Rohit Prakash, Thomas Sandoval, Florian Morati…·Maria Jasin

This study identifies the SWS1-SWSAP1-SPIDR complex as a regulator of distinct homologous recombination pathways, with specific roles in inter-homolog HDR and cancer-related genomic instability.

50 citations

mouseexperimental assay

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