Mario Costa

This study shows that activating GABAergic circuits with baclofen enhances the effectiveness of anti-PD-L1 immunotherapy in glioblastoma, leading to tumor regression and prolonged survival in mice.

This study compares FLASH and conventional radiotherapy effects on white adipose tissue, finding FLASH better preserves tissue function and structure while conventional RT causes metabolic and inflammatory changes.

This study compares FLASH and conventional radiotherapy in melanoma-bearing and naive mice, finding FLASH reduces long-term tissue damage and systemic inflammation while maintaining tumor control.

This study shows that SARS-CoV-2 infection causes Tau phosphorylation and aggregation in neurons, linked to Alzheimer's disease pathology.

The paper shows that mechanical stimulation via magnetic nano-pulling accelerates neural precursor maturation into neurons and alters neuronal network organization.

This study investigates how congenital pain insensitivity in heterozygous humans and mice affects affective pain responses, finding dissociated effects on learned fear and neural processing.