Zhewei Zhang

Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex

This study shows that prior cocaine use impairs the orbitofrontal cortex's ability to identify hidden states during a task, leading to reduced generalization and increased behavioral variability.

Dopaminergic responses to identity prediction errors depend differently on the orbitofrontal cortex and hippocampus

This study shows that dopamine neuron prediction error signaling for reward value and identity depends differently on the hippocampus and orbitofrontal cortex in rats.

Post-inhibitory rebound firing drives hypothalamic activation for male mating

The paper identifies post-inhibitory rebound firing as a mechanism by which inhibition promotes activation in limbic circuits to drive male mating.

Dopamine and acetylcholine correlations in the nucleus accumbens depend on behavioral task states

The paper examines dopamine and acetylcholine correlations in the nucleus accumbens during a behavioral task in rats, finding their relationship varies based on task phases.

Sequential recruitment of accumbal dopamine and acetylcholine during learning

This study investigates how dopamine and acetylcholine dynamics change during learning in rats, finding that acetylcholine signals evolve sequentially and complement dopamine in determining learning content and rate.

Three-dimension transcriptomics maps of whole mouse embryo during organogenesis

The paper fills a gap in 3D spatial transcriptomics by providing data from E9.5 and E11.5 mouse embryos, enabling detailed analysis of organogenesis with a new open-access database.

Expectancy-related changes in firing of dopamine neurons depend on hippocampus

This study shows that hippocampal lesions affect dopamine neuron firing patterns during a reward prediction task, contrasting with the role of the orbitofrontal cortex.

Schema cell formation in orbitofrontal cortex is suppressed by hippocampal output

This study investigates how hippocampal output affects schema formation in orbitofrontal cortex, finding that inactivation during learning accelerates schema correlates while post-learning inactivation has no effect, supporting a parallel model of cognitive map formation.

A Recurrent Neural Network Model for Flexible and Adaptive Decision Making based on Sequence Learning

This paper develops a recurrent neural network model for decision making that mimics animal behavior and neural activity patterns in tasks involving sensory input, action, and reward.

Orbitofrontal control of visual cortex gain promotes visual associative learning

This study shows that OFC projections to V1 modulate visual response gain to non-relevant stimuli, facilitating visual associative learning.

A neural network model for the orbitofrontal cortex and task space acquisition during reinforcement learning

This paper introduces a neural network model based on reservoir computing to simulate how the orbitofrontal cortex acquires and stores task state information during reinforcement learning.