Guochuan Li

This study shows that cholinergic modulation between brain hemispheres enables paw preference switching in mice through experience-driven changes in neural activity.

The paper shows acetylcholine release in the retrosplenial cortex correlates with changes in expected uncertainty and influences neuronal representation shifts and learning speed in mice.

The paper develops red-shifted GRAB acetylcholine sensors for multiplex imaging of ACh and other neuromodulators in vivo with high spatiotemporal resolution.

The paper identifies a thalamostriatal circuit mechanism by which internally constructed outcomes, like safety, acquire motivational value through synaptic plasticity in mice.

This study investigates how phase synchrony between prefrontal noradrenergic and cholinergic signals relates to inhibitory control in mice.

The paper introduces a far-red dopamine sensor, HaloDA1.0, enabling multiplex imaging of neurochemical networks in vivo with high sensitivity and versatility.

The paper examines dopamine and acetylcholine correlations in the nucleus accumbens during a behavioral task in rats, finding their relationship varies based on task phases.

The paper examines cortical acetylcholine dynamics during behavioral state transitions, finding that axon activity and behavior predict ACh levels.

This study investigates the role of acetylcholine in shaping stable olfactory representations across the Drosophila brain using advanced imaging techniques and network analysis.

The paper develops improved GRABDA sensors to monitor dopaminergic activity in vivo, showing high sensitivity and spatially resolved DA release in mice during behaviors.

The paper develops GRAB sensors for detecting neuropeptides with high specificity and sensitivity, enabling in vivo monitoring of their release and function.

This paper develops dual-color GRAB sensors to monitor spatiotemporal serotonin release in vivo, revealing uniform and gradient release patterns and seizure-induced waves.

This paper develops genetically encoded sensors to measure histamine release in vitro and in vivo, showing high sensitivity and specificity for extracellular histamine detection.