Author

Sasha Shirman

Northwestern UniversityORCID 0000-0001-5855-9470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Biochemistry· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Assay:metabolomics· 1

Frequent Co-Authors

Niall M. ManganiD· 4 shared Michael C. JewettiD· 3 shared Carolyn E. MillsiD· 2 shared Charlotte H. AbrahamsoniD· 2 shared Danielle Tullman‐ErcekiD· 2 shared Andre G. Archer· 1 shared Anne E. d’AquinoiD· 1 shared Brett PalmeroiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersSynthetic Biology

Niall M. ManganORCID

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 20, 2025

Evaluation of Bacterial Microcompartment Cofactor Recycling and Permeability with a Model Guided In Vitro Assay

Brett Palmero, Christina Catlett, Charlotte H. Abrahamson…·Danielle Tullman‐Ercek

The paper evaluates cofactor recycling and permeability in bacterial microcompartments using an in vitro assay and kinetic model of the Pdu system, showing benefits for pathway flux.

1 citation

bacteria (other)metabolomics

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedDec 13, 2024

Developing, characterizing and modelingCRISPR-based point-of-use pathogen diagnostics

Jaeyoung Kirsten Jung, Kathleen S. Dreyer, Kate E. Dray…·Julius B. Lucks

The paper develops and optimizes a one-pot NASBA-Cas13a assay for rapid, sensitive detection of SARS-CoV-2 RNA without specialized equipment.

13 citations

experimental assay

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Synthetic BiologyJournal of BacteriologyPeer-reviewedMay 16, 2022

Linking the Salmonella enterica 1,2-propanediol utilization bacterial microcompartment shell to the enzymatic core via the shell protein PduB

Nolan W. Kennedy, Carolyn E. Mills, Charlotte H. Abrahamson…·Danielle Tullman‐Ercek

This study identifies PduB as the protein linking the 1,2-propanediol utilization MCP shell to its enzymatic core in Salmonella, showing shell and core assembly are separate processes.

23 citations

bacteria (other)experimental assay

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Developmental BiologyCells and DevelopmentPeer-reviewedJan 1, 2022

Changes in body shape implicate cuticle stretch in C. elegans growth control

Joy Nyaanga, Christina Goss, Gaotian Zhang…·Erik C. Andersen

The paper measures body shape and growth in C. elegans during development, finds shape changes without volume change, and models cuticle stretch as a mechanism for growth control.

21 citations

C. elegansimaging

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