Yuan Wang

scGSCA analyzes single-cell RNA sequencing data to detect differential gene-set co-expression across phenotypes, identifying pathway changes missed by bulk methods.

This study investigates thalamocortical network dynamics in focal epilepsy using SEEG data, finding that thalamic aperiodic slope changes correlate with seizure propagation and feedback mechanisms.

The paper describes the assembly of a chemogenetic library through data mining and crowdsourcing, sharing 4186 compounds with annotated gene targets.

The paper develops tools to compare and design optimized small molecule libraries using chemical and biological data, resulting in a more effective kinase inhibitor library.