Hiromu Tanimoto

The paper characterizes neuropeptide T2A-GAL4 knock-in lines in Drosophila, showing that adult GAL4 reporter patterns may not reflect ongoing activity and can have developmental effects.

The paper uses optogenetic stimulation and Ribo-seq in Drosophila to show that neuronal activity triggers two phases of translation: one for synaptic factors and another for ribosomal proteins, regulated by TOP motifs and La-related protein.

The paper identifies a bidirectional communication pathway between the fat body and the nervous system that drives pathogen avoidance behavior in response to immune receptor signaling.

The paper uses split-GFP reconstitution to profile presynaptic scaffold protein configurations in fly brain neurons, revealing cell-type-specific spatial patterns and learning-induced plasticity.

The paper shows octopamine signaling coordinates presynaptic machinery spatial patterns in Drosophila mushroom body neurons through Octβ2R and cAMP signaling, influenced by food deprivation.

This study shows that gut microbiota-mediated lipid accumulation, through midgut elongation, enables Drosophila to adapt to blue light toxicity over generations.

This study identifies neuropeptide signalling and perineurial barrier activation as mechanisms underlying persistent stress-induced behavioral changes in Drosophila.

The paper examines the expression and localization of two opposing dopamine receptors in Drosophila neurons, revealing their presynaptic enrichment and starvation-dependent regulation.

This study shows that Chameau (HBO1) enhances starvation resilience in Drosophila melanogaster at lower temperatures, but its role diminishes at higher temperatures.

The paper shows that translational regulation, particularly through 5' leader uORFs, enhances cell-type distinction in the Drosophila nervous system by preferentially translating neuronal proteins in neurons.

This study identifies a descending inhibitory mechanism of nociception in Drosophila mediated by the evolutionarily conserved neuropeptide DSK, analogous to the mammalian CCK system.

This study identifies octopamine signaling from efferent neurons as essential for mating-induced germline stem cell proliferation in female Drosophila.

This study shows environmental light is essential for long-term memory maintenance in Drosophila by activating CREB in mushroom bodies via the Pdf signaling pathway.

The paper develops a method to classify neural activity in Drosophila larvae and identifies 5-HT2A neurons involved in backward locomotion.