Toshiharu Ichinose

Neuronal stop-codon readthrough is associated with ribosome pausing and appends lineage-restricted extensions that can alter protein localization in Drosophila

The paper identifies neuronal stop-codon readthrough in Drosophila, showing it produces C-terminal extensions that alter protein localization.

Activity-dependent synthesis of translational machinery through dynamic remodeling of ribonucleoprotein granules

The paper uses optogenetic stimulation and Ribo-seq in Drosophila to show that neuronal activity triggers two phases of translation: one for synaptic factors and another for ribosomal proteins, regulated by TOP motifs and La-related protein.

An Innate Immune Receptor Toll-1 converts chronic light stress into glial-phagocytosis

This study identifies a neuron-glia signaling axis where Toll-1 converts chronic light stress into glial-phagocytosis, leading to axonal degeneration.

Gut microbiota-mediated lipid accumulation as a driver of evolutionary adaptation to blue light toxicity in Drosophila

This study shows that gut microbiota-mediated lipid accumulation, through midgut elongation, enables Drosophila to adapt to blue light toxicity over generations.

Chameau (HBO1) regulates starvation in a temperature-dependent manner in Drosophila melanogaster

This study shows that Chameau (HBO1) enhances starvation resilience in Drosophila melanogaster at lower temperatures, but its role diminishes at higher temperatures.

Translational regulation enhances distinction of cell types in the nervous system

The paper shows that translational regulation, particularly through 5' leader uORFs, enhances cell-type distinction in the Drosophila nervous system by preferentially translating neuronal proteins in neurons.