E. Jane Albert Hubbard

Non-autonomy of age-related morphological changes in the C. elegans germline stem cell niche

The paper examines age-related morphological changes in the C. elegans germline stem cell niche and identifies non-autonomous regulation by insulin/IGF-like signaling.

Intestinal RICT-1/Rictor regulates larval germline progenitors via vitellogenins VIT-1 and VIT-3 in C. elegans

The paper shows that RICT-1/Rictor in C. elegans promotes larval germline development via TORC2 signaling and vitellogenins VIT-1 and VIT-3.

Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool

The paper shows that gap-junctional signaling via innexins controls the positioning of distal somatic cells in C. elegans gonads without affecting germline stem cell boundaries.

Modeling the C. elegans Germline Stem Cell Genetic Network using Automated Reasoning

The paper models the C. elegans germline stem cell genetic network using formal reasoning to predict regulatory interactions and cellular decision-making.

DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence

This study shows that DAF-18/PTEN maintains quiescence in primordial germ cells by inhibiting zygotic gene activation and cell division during starvation.

Intergenerational effects of dietary restriction on insulin/IGF signaling and reproductive development

This study investigates how maternal dietary restriction affects reproductive development in C. elegans by modulating insulin/IGF signaling, reducing starvation-induced abnormalities in progeny.