Jonathan D. Hibshman

This study identifies DUR-1, a secreted LEA-like protein in C. elegans, as a basement membrane component that enhances tissue integrity and stress survival.

The paper identifies tardigrade mitochondrial single-stranded DNA-binding proteins as effective desiccation protectants through a bacterial expression cloning screen.

Tardigrades upregulate DNA repair genes after ionizing radiation, enhancing their radiation tolerance.

This study investigates the role of LEA-1 protein in desiccation tolerance in C. elegans, showing its protective effects against multiple stresses and identifying functional motifs that can be applied across species.

The paper introduces new tools for the auxin-inducible degron system in C. elegans, enabling conditional protein depletion through CRISPR/Cas9-mediated genome editing.

This study investigates how maternal dietary restriction affects reproductive development in C. elegans by modulating insulin/IGF signaling, reducing starvation-induced abnormalities in progeny.