Yizhi Sun

This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.

This study maps zinc-regulated cysteine sites in the human proteome, identifies cancer dependencies, and reveals a mechanism of zinc-induced cytotoxicity in lung cancers.

This study identifies MPST as the direct target of EGT, showing it enhances mitochondrial respiration and exercise performance in mice.