Wei Li

This study identifies LRRC37A as critical for acrosomal ion homeostasis, showing its loss leads to male infertility and acrosomal enlargement.

The paper investigates genetic and physical interactions of DSB factors in C. elegans, revealing HIM-5's role in X-chromosome-specific crossovers and its dependency on DSB-1.

The paper shows that testis-specific 20S proteasome core particles in sperm help prevent polyspermy by forming chimeric proteasomes that degrade Fetuin B, leading to zona pellucida hardening.

This study investigates how Cyclina sinensis lectin affects yeast metabolism, showing it enhances ethanol production by altering glycolytic and TCA cycle enzyme expression and metabolite levels.

This study identifies CCDC113 as a critical protein for stabilizing sperm axoneme and head-tail coupling apparatus, linking its disruption to male infertility.

The paper shows that CCDC38 is essential for sperm flagellum formation and male fertility in mice, with its deficiency causing structural abnormalities and sterility.

This study identifies CFAP53 as essential for sperm flagellum biogenesis, showing its role in male infertility and interactions with proteins in the manchette and sperm tail.

This study identifies ZCWPW1 as an H3K4me3 reader required for DSB repair and synapsis in mouse testes, showing its dependency on PRDM9 activity.

The paper identifies GCNA as a conserved regulator of genome stability in germ cells across species, showing its role in preventing DNA damage and maintaining fertility.

This study investigates the roles of ATM-1 and ATL-1 in meiotic crossover formation in C. elegans, showing their antagonistic and overlapping functions in regulating repair template choice and RAD-51 accumulation.