Author

Jennifer Patritti Cram

Cincinnati Children's Hospital Medical CenterORCID 0000-0001-5971-0849Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Nancy RatneriD· 2 shared Tilat A. RizviiD· 2 shared Aaditya Adlakha· 1 shared Ashley R. Rupert· 1 shared Irati Mitxelena· 1 shared Jianqiang WuiD· 1 shared Jose A. Cancelas· 1 shared Katherine E. Chaney· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Nancy RatnerORCID

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2 papers

Recent·Most cited

NeuroscienceJCI InsightPeer-reviewedJan 22, 2024

Schwann cells modulate nociception in neurofibromatosis 1

Namrata G.R. Raut, Laura A. Maile, Leila M. Oswalt…·Michael P. Jankowski

The paper shows that Schwann cell Nf1 loss causes mechanical pain via GDNF release, which affects adjacent neurons, suggesting cell-specific treatment strategies for NF1-related pain.

12 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedMar 21, 2022

Purinergic receptor P2RY14 cAMP signaling regulates EGFR-driven Schwann cell precursor self-renewal and nerve tumor initiation in neurofibromatosis.

Jennifer Patritti Cram, Jianqiang Wu, Shinji Kuninaka…·Nancy Ratner

This study identifies P2RY14 as a regulator of cAMP signaling in Schwann cell precursors, showing its role in self-renewal and neurofibroma initiation in NF1 mutant cells.

19 citations

mousestatistical model

𝕏 PostBluesky