Author

Markella Konstantinidou

University of California, San FranciscoORCID 0000-0001-5972-4140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Christian OttmanniD· 2 shared Emira J. VisseriD· 2 shared Johanna M. VirtaiD· 2 shared Luc BrunsveldiD· 2 shared Michelle R. ArkiniD· 2 shared Bente A. SomseniD· 1 shared Damir VarešlijaiD· 1 shared Frank P. McCormickiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

Christian OttmannORCID

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2 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedJan 30, 2026

Modulation of the 14-3-3σ/C-RAF autoinhibited complexby molecular glues

Markella Konstantinidou, Holly R. Vickery, Marloes A. M. Pennings…·Michelle R. Arkin

This paper designs molecular glues that stabilize the 14-3-3/C-RAF autoinhibited complex, showing selectivity and functional effects in biophysical and cell assays.

6 citationstop 2%

deep learningdrug response / drug discovery

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Cancer BiologybioRxivPreprintApr 25, 2024

Estrogen Receptor alpha/14-3-3 molecular glues as alternative treatment strategy for endocrine resistant breast cancer

Emira J. Visser, Maria Donaldson Collier, Joseph C. Siefert…·Luc Brunsveld

This study investigates molecular glues targeting the ER/14-3-3 PPI to overcome endocrine resistance in breast cancer, showing suppression of ER activity and cell proliferation.

6 citations

humanproteomics

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