Author

Marloes A. M. Pennings

Eindhoven University of TechnologyORCID 0000-0002-3366-0238Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Christian OttmanniD· 2 shared Emira J. VisseriD· 2 shared Luc BrunsveldiD· 2 shared Donald K. ScottiD· 1 shared Frank P. McCormickiD· 1 shared Holly R. Vickery· 1 shared Isabelle Tse· 1 shared Johanna M. VirtaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Christian OttmannORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedJan 30, 2026

Modulation of the 14-3-3σ/C-RAF autoinhibited complexby molecular glues

Markella Konstantinidou, Holly R. Vickery, Marloes A. M. Pennings…·Michelle R. Arkin

This paper designs molecular glues that stabilize the 14-3-3/C-RAF autoinhibited complex, showing selectivity and functional effects in biophysical and cell assays.

6 citationstop 2%

deep learningdrug response / drug discovery

𝕏 PostBluesky

Cell BiologyNature CommunicationsPeer-reviewedMar 2, 2025

Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity.

Liora S. Katz, Emira J. Visser, Kathrin Plitzko…·Donald K. Scott

This paper identifies molecular glues that stabilize the ChREBP/14-3-3 complex, protecting beta cells from glucolipotoxicity by preventing ChREBP-mediated dedifferentiation.

32 citationstop 2%

humanexperimental assay

𝕏 PostBluesky